What is acute lymph
Acute lymphoid (acute lymphoblastic leukemia, ALL) is a common hematologic malignancy that occurs primarily in children and adolescents, but adults may also be affected. In recent years, with the deepening of medical research, the treatment methods and prognosis of acute lymphoma have been significantly improved. This article will combine the hot topics and hot content on the Internet in the past 10 days to introduce in detail the definition, symptoms, diagnosis, treatment and latest research progress of acute lymphadenitis.
1. Definition of acute lymphoid
Acute lymphoblastic leukemia (ALL) is a malignant disease caused by abnormal proliferation of immature lymphocytes in the bone marrow. These abnormal cells quickly replace normal blood-forming cells, causing symptoms such as anemia, infection, and bleeding. According to the different sources of cells, ALL can be divided into B cell type and T cell type.
2. Symptoms of acute lymphadenitis
Common symptoms of acute lymphadenitis include:
| Symptoms | Description |
|---|---|
| anemia | Pale complexion, fatigue, dizziness |
| infection | Recurrent fever, mouth ulcers, pneumonia |
| bleeding | Skin ecchymoses, nosebleeds, gum bleeding |
| swollen lymph nodes | Swollen lymph nodes in the neck, armpit, or groin |
| bone pain | pain in your limbs or back |
3. Diagnosis of acute lymphadenitis
The diagnosis of acute lymphadenitis requires a combination of clinical manifestations and laboratory tests, which mainly include:
| Check items | meaning |
|---|---|
| Blood routine | Test the number of white blood cells, red blood cells and platelets |
| bone marrow aspiration | Confirm the presence and type of leukemia cells |
| immunophenotyping | Determine the source of leukemia cells (B cells or T cells) |
| Chromosome and genetic testing | Assess prognosis and guide treatment |
4. Treatment of acute lymphoma
The treatment of acute lymphoblastic lymphoma mainly includes chemotherapy, targeted therapy, immunotherapy and hematopoietic stem cell transplantation. The following are common treatments:
| Treatment | Description |
|---|---|
| Chemotherapy | Killing leukemia cells through drugs, divided into induction, consolidation and maintenance stages |
| targeted therapy | Targeted drugs that target specific gene mutations (such as BCR-ABL) |
| Immunotherapy | New treatments such as CAR-T cell therapy |
| Hematopoietic stem cell transplantation | Suitable for high-risk or relapsed patients |
5. Latest research progress
Recently, research on acute lymphoblastic lymphoma has mainly focused on the fields of new targeted drugs and immunotherapy. The following are popular research topics in the past 10 days:
| Research areas | progress |
|---|---|
| CAR-T cell therapy | Breakthrough in clinical trial for relapsed/refractory ALL |
| bispecific antibodies | Drugs like Blinaumomab significantly improve response rates |
| gene editing | CRISPR technology used to optimize CAR-T cell therapy |
| Minimal residual disease (MRD) | MRD detection technology helps precise treatment |
6. Prevention and prognosis
At present, the cause of acute lymphadenitis is not fully understood, but avoiding exposure to radiation and chemical poisons may reduce the risk of the disease. In terms of prognosis, the cure rate of childhood ALL can reach 90%, and the cure rate of adult ALL is about 40%-50%. Early diagnosis and standardized treatment are the keys to improving prognosis.
Conclusion
Acute lymphadenitis is a curable disease, but as medical technology advances, new treatments bring more hope to patients. If you or your family members have relevant symptoms, please seek medical treatment in time. Early diagnosis and early treatment are the keys to defeating the disease.
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